Course Description
The number of oropharyngeal and anal cancers linked to human papillomavirus (HPV) has risen dramatically over the past few decades. HPV-positive (HPV+) cancers are epidemiologically distinct from HPV negative cancers. HPV+ oropharyngeal cancers are characterized by younger age of onset, less exposure to alcohol, and higher socioeconomic status and education. Anal cancer is an uncommon malignancy. However, an increased incidence has been associated with female gender, infection with HPV, lifetime number of sexual partners, genital warts, cigarette smoking, receptive anal intercourse, and infection with human immunodeficiency virus. Multimodality imaging, including PET, MRI, and PET/CT, plays an important role in the diagnosis, primary staging, treatment planning and post-treatment evaluation and follow-up in these HPV+ cancers. Understanding the benefits of various imaging modalities in the management of these cancers may provide important prognostic information to enhance patient outcomes.

Learning Objectives
After reading this article, the participant should be able to:

Categories: Nuclear Medicine, Radiation Therapy/Dosimetry