

Course Description
Breast cancer is the second-most common cause of cancer-related deaths in women and can sometimes be detected on self-examinations before any symptoms appear. Mammography continues to be the gold standard in breast cancer screening as it can visualize lesions that appear as macrocalcifications (with or without a mass) that are nonpalpable on self-examinations. Breast calcifications are a common finding on screening mammograms and can be an early sign of breast cancer. To determine if breast calcifications are benign or malignant, a precise, targeted biopsy of the tissue, guided by the Breast Imaging Reporting and Data System (BI-RADS), may be performed to provide further critical diagnostic information. This histopathological analysis, combined with the mammographic images, can prevent patients from undergoing unnecessary procedures. This journal-article-based, continuing education course will review the decision-making process regarding biopsies after mammographic analysis using the BI-RADS system. Different breast biopsy procedures will be reviewed along with histopathological classifications, emphasizing the role of vacuum-assisted breast biopsy under stereotactic guidance. Ten complex cases, with images and histopathological analysis, will be presented and reviewed, which will highlight the critical diagnostic steps involved in clinical decision-making.
Learning Objectives
After reviewing the content, the participant should be able to:
Categories: Radiography, Mammography

In order to receive CE credit, you must first complete the activity content. When completed, go to the "Take CE Test!" link to access the post-test.
Submit the completed answers to determine if you have passed the post-test assessment. You must answer 8 out of 10 questions correctly to receive CE credit. You will have no more than 3 attempts to successfully complete the post-test.
Participants successfully completing the activity content and passing the post-test will receive 1.0 ARRT Category A credits.
Approved by the American Society of Radiologic Technologists for ARRT Category A credit.
Approved by the state of Florida for ARRT Category A credit.
Texas direct credit.
This activity may be available in multiple formats or from different sponsors. ARRT does not allow CE activities such as Internet courses, home study programs, or directed readings to be repeated for CE credit in the same biennium.

| Category | Content Area | Credits |
|---|---|---|
| Breast Sonography | Patient Care | 0.25 |
| Breast Sonography | Procedures | 0.75 |
| Mammography | Procedures | 1 |
| Radiologist Assistant | Procedures | 0.25 |
| Radiologist Assistant | Safety | 0.25 |
| Sonography | Procedures | 0.75 |

| Category | Subcategory | Credits |
|---|---|---|
| Breast Sonography | Breast Interventions | 0.75 |
| Breast Sonography | Patient Interactions and Management | 0.25 |
| Mammography | Anatomy, Physiology and Pathology | 0.25 |
| Mammography | Mammographic Positioning and Procedures | 0.75 |
| Radiologist Assistant | Patient Safety, Radiation Protection and Equipment Operation | 0.25 |
| Radiologist Assistant | Thoracic Section | 0.25 |
| Sonography | Superficial Structures and Other Sonographic Procedures | 0.75 |

| Category | Credits |
|---|---|
| Digital | 0.75 |
| Fluoroscopy | 0 |
| Mammography | 0.75 |
By Jana Bebek; Nikolina Novak; Marina Dasovic; Eugen Divjak; Cedna Tomasovic-Loncaric; Boris Brkljacic; and Gordana Ivanac
ABSTRACT
Breast cancer is the second-most common cause of cancer-related deaths in women and can sometimes be detected on self-examinations before any symptoms appear. Mammography continues to be the gold standard in breast cancer screening as it can visualize lesions that appear as macrocalcifications (with or without a mass) that are nonpalpable on self-examinations. Breast calcifications are a common finding on screening mammograms and can be an early sign of breast cancer. To determine if breast calcifications are benign or malignant, a precise, targeted biopsy of the tissue, guided by the Breast Imaging Reporting and Data System (BI-RADS), may be performed to provide further critical diagnostic information. This histopathological analysis, combined with the mammographic images, can prevent patients from undergoing unnecessary procedures. This journal-article-based, continuing education course will review the decision-making process regarding biopsies after mammographic analysis using the BI-RADS system. Different breast biopsy procedures will be reviewed along with histopathological classifications, emphasizing the role of vacuum-assisted breast biopsy under stereotactic guidance. Ten complex cases, with images and histopathological analysis, will be presented and reviewed, which will highlight the critical diagnostic steps involved in clinical decision-making.
EDITORIAL NOTE: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/), which has not been altered.
Original publication: Bebek J, Novak N, Dasovic M, et al. Histopathological analysis of vacuum-assisted breast biopsy in relation to microcalcification findings on mammography: a pictorial review. Biomedicines. 2025;13:737-756.
* This sample course is for reference purposes only. It is not currently available for earning CE credits. To earn ARRT CE credits please subscribe to eRADIMAGING where you will see a complete listing of all active and eligible CE courses.
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