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Contrast-Enhanced Spectral Mammography: Current Indications, Future Applications, and Cost-Effectiveness
*President, MedCom Consultants, Inc, Potomac MD
Address correspondence to: Steven Marks, MedCom Consultants Inc, 1311 Fallsmead Way, Potomac MD 20854. Email: firstname.lastname@example.org
Disclosure statement: Steven Marks reports having no financial or advisory relationship with any corporate, medical, or political organization doing work related to this paper or other business activity at MedCom Consultanadts, Inc.
Screening mammography is a proven means to reduce mortality from breast cancer. Full-field digital mammography (FFDM), a computer-based imaging system that has replaced conventional analog-film technology, is limited by relatively poor sensitivity in most subgroups of the screening population. A new imaging technique, contrast-enhanced spectral mammography (CESM), combines low-energy 2-dimensional mammography with a high-energy image. The resulting images generate highly sensitive and specific pictures that visualize tumor neovascularity with accuracy comparable to magnetic resonance imaging (MRI). CESM is a cost-effective and convenient tool for the diagnosis and management of patients with breast cancer and is now being used in indications customarily reserved for MRI. It also is being evaluated in potential new applications, including subgroups at high risk for disease.
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